This book constitutes the proceedings of the Second International Conference on Smart Multimedia, ICSM 2019, which was held in San Diego, CA, USA, in December 2019. The 45 papers presented were selected from about 100 submissions and are grouped in sections on 3D mesh and depth image processing; image understanding; miscellaneous; smart multimedia for citizen-centered smart living; 3D perception and applications; video applications; multimedia in medicine; haptics and applications; smart multimedia beyond the visible spectrum; machine learning for multimedia; image segmentation and processing; biometrics; 3D and image processing; and smart social and connected household products.