Dearomatization is a fundamental chemical transformation of arenes, involving some of the most efficient tactics for rapid and selective generation of complexity from simple aromatic compounds. Once limited to a handful of reactions, the toolbox of dearomative chemistry has expanded significantly over the past two decades. Today, more sophisticated methods allow for the incorporation of diverse functionalities under milder conditions. This Science of Synthesis volume serves as an essential reference, covering all aspects of dearomative chemistry, from classic transformations such as the Birch reduction to cutting-edge developments in asymmetric catalysis, photochemistry, and electrochemistry. In addition to providing a broad overview of the landscape, particular emphasis is placed on practical methods that provide enhanced control over chemo-, regio-, and stereoselectivity.
